Pain, Quality of Life, and Functional Capacity With Topical Sevoflurane Application for Chronic Venous Ulcers: A Retrospective Clinical Study.

INTRODUCTION: Chronic venous ulcers (CVU) commonly have poorly controlled pain. REPORT: Thirty patients older than 65 years of age with painful CVU were reviewed. At the initial visit, cleaning without sevoflurane was performed. Cleaning visits with sevoflurane every 2 days for 1 month were scheduled. The results of subsequent treatment with sevoflurane at the first, second, seventh, and twelfth cleanings were analysed. Pain was measured using a visual analog scale (VAS), quality of life by the Charing Cross Venous Leg Ulcer Questionnaire, and functional capacity by the Barthel Index. DISCUSSION: Initial VAS was 8.8 ± 1.3 points and at the twelfth cleaning VAS was 0.8 ± 1 points (p = .001). Latency time ranged between 2 and 7 m and duration ranged between 8 and 18 h. It improved quality of life (83 ± 14 points before treatment vs. 50 ± 14 at the twelfth cleaning) and functional capacity (82 ± 13.3 before treatment vs. 91 ± 11.6 points at the twelfth cleaning) (p = .001). The safety profile was favourable with mild and self limited local cutaneous adverse effects, including pruritus, erythema, and heat. No systemic toxicity was detected. Topical sevoflurane may be a therapeutic alternative for painful CVU with a fast, intense, and long-lasting analgesic effect.

Eczema alérgico de contacto por resina epoxi / Allergic contact eczema from epoxy resin

Las resinas epoxi son plásticos muy empleados como aislantes eléctricos, en recubrimientos y como adhesivos y pinturas. Presentan un gran poder sensibilizante y son una de las principales causas de eczema alérgico de contacto, tanto en el medio laboral como fuera de éste. Presentamos el caso de un trabajador de una planta plastoquímica que manipulaba componentes de material aeronáutico en el proceso de fabricación de piezas de fuselaje. Consultó por lesiones eczematosas en los dedos, manos y antebrazos, de 2 años de evolución, en clara relación con su actividad laboral. Se realizaron pruebas epicutáneas con la batería estándar, la de plásticos y adhesivos y sus productos propios. Se objetivaron positividades a resinas epoxi (batería estándar) y a sus productos propios, entre los que se encontraban distintas láminas de fibras de vidrio y carbono impregnadas con resinas epoxi y adhesivos epoxi

Epoxy resins are plastics that are widely used as electrical insulation, in coatings, and as adhesives and paints. They have strong sensitizing power and are one of the main causes of allergic contact eczema, both in the workplace and elsewhere. We present the case of a worker at a plastics/ chemical plant, who handled aeronautical components in the process of manufacturing fuselage parts. He consulted his physician because of eczematous lesions on his fingers, hands and forearms which had developed over a two-year period and were clearly related to his work. The standard battery of skin tests was performed, along with the plastics and adhesives series and tests using the products from his workplace. Positivity was shown to epoxy resins (standard battery) and to the products from his workplace, which included different fiberglass and carbon fiber sheets impregnated with epoxy resins and epoxy adhesives

Eczema alérgico de contacto profesional en auxiliar de odontología / Occupational allergic contact eczema in a dental assisstant

La frecuencia de eczemas de contacto profesional es muy elevada en auxiliares de dentistas. Se presenta el caso de una mujer de 46 años con lesiones pruriginosas eritematoedematosas, escamosas, de límites imprecisos en dorso y laterales de dedos de manos de varios meses de evolución. Las pruebas epicutáneas realizadas con la batería estándar del GEIDC, la dental de Chemotechnique y sus productos propios demostraron positividades para sulfato de níquel, cloruro de cobalto, dicromato potásico, tiosulfato sódico de oro, eugenol, el líquido de endodoncia denominado «eugenol», mezcla de fragancias y colofonia. El eugenol es un producto perfumado que se emplea en cementos y sellantes de endodoncia y periodontología. Hay cinco artículos con casos de eczema alérgico de contacto profesional por este producto en dentistas o enfermeras y auxiliares que trabajan en clínicas dentales

Occupational contact eczemas are very frequent in dental assistants. We present the case of a 46-year-old woman with pruritic, flaky, erythematous-edematous lesions, with indistinct borders, on the backs and sides of the fingers, which had been developing for several months. The skin tests performed with the GEIDC (Spanish Contact Dermatitis Research Group) standard battery, the Chemotechnique dental screening series and her own products showed positivity to nickel sulfate, cobalt chloride, potassium dichromate, gold sodium thiosulfate, the liquid used in endodontics known as «eugenol,» fragrance mix and colophony. Eugenol is a perfumed product that is used in cements and sealants for endodontics and periodontology. There are 5 articles regarding cases of occupational allergic contact eczema from this product in dentists or nurses and assistants who work in dental clinics

[Allergic contact eczema from epoxy resin]. / Eczema alérgico de contacto por resina epoxi.

Epoxy resins are plastics that are widely used as electrical insulation, in coatings, and as adhesives and paints. They have strong sensitizing power and are one of the main causes of allergic contact eczema, both in the workplace and elsewhere. We present the case of a worker at a plastics/chemical plant, who handled aeronautical components in the process of manufacturing fuselage parts. He consulted his physician because of eczematous lesions on his fingers, hands and forearms which had developed over a two-year period and were clearly related to his work. The standard battery of skin tests was performed, along with the plastics and adhesives series and tests using the products from his workplace. Positivity was shown to epoxy resins (standard battery) and to the products from his workplace, which included different fiberglass and carbon fiber sheets impregnated with epoxy resins and epoxy adhesives.

[Occupational allergic contact eczema in a dental assistant]. / Eczema alérgico de contacto profesional en auxiliar de odontología.

Occupational contact eczemas are very frequent in dental assistants. We present the case of a 46-year-old woman with pruritic, flaky, erythematous-edematous lesions, with indistinct borders, on the backs and sides of the fingers, which had been developing for several months. The skin tests performed with the GEIDC (Spanish Contact Dermatitis Research Group) standard battery, the Chemotechnique dental screening series and her own products showed positivity to nickel sulfate, cobalt chloride, potassium dichromate, gold sodium thiosulfate, the liquid used in endodontics known as "eugenol," fragrance mix and colophony. Eugenol is a perfumed product that is used in cements and sealants for endodontics and periodontology. There are 5 articles regarding cases of occupational allergic contact eczema from this product in dentists or nurses and assistants who work in dental clinics.